Ivan Dikic Selected Research

Ubiquitin

12/2022	Ubiquitin and Legionella: From bench to bedside.
1/2018	Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
1/2018	Regulation of Salmonella-host cell interactions via the ubiquitin system.
1/2016	An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis.
1/2016	Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection.
12/2014	Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis.
5/2014	Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling.
4/2014	Germline polymorphisms in RNF31 regulate linear ubiquitination and oncogenic signaling.
11/2013	Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
7/2012	Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ivan Dikic Research Topics

Disease

27	Neoplasms (Cancer) 01/2022 - 01/2002
15	Inflammation (Inflammations) 01/2022 - 02/2008
10	Infections 12/2022 - 01/2016
6	Necrosis 12/2014 - 01/2002
4	Salmonella Infections (Salmonellosis) 11/2021 - 01/2016
4	COVID-19 05/2021 - 11/2020
4	Starvation 05/2017 - 07/2009
3	Bacterial Infections (Bacterial Infection) 11/2021 - 01/2018
3	Glioma (Gliomas) 07/2021 - 04/2016
2	Fanconi Anemia (Fanconi's Anemia) 01/2022 - 09/2011
2	Carcinogenesis 10/2021 - 12/2006
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 01/2007
2	Parkinson Disease (Parkinson's Disease) 01/2013 - 02/2010
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2013 - 10/2008
2	Hypercapnia 07/2005 - 11/2002
1	MYD88 Deficiency 10/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2021
1	Glioblastoma (Glioblastoma Multiforme) 07/2021
1	Cytokine Release Syndrome 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 10/2020
1	Genomic Instability 01/2020
1	Reperfusion Injury 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2018
1	Triple Negative Breast Neoplasms 01/2018
1	Colitis 01/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2017
1	Proteinuria 12/2016
1	Edema (Dropsy) 12/2016
1	Diabetic Nephropathies (Diabetic Nephropathy) 12/2016
1	Hypoxia (Hypoxemia) 04/2016
1	Sepsis (Septicemia) 01/2016

Drug/Important Bio-Agent (IBA)

24	UbiquitinIBA 12/2022 - 05/2006
14	Proteins (Proteins, Gene)FDA Link 10/2021 - 07/2005
6	Phosphotransferases (Kinase)IBA 11/2021 - 07/2007
5	Transcription Factors (Transcription Factor)IBA 01/2022 - 07/2005
4	Deubiquitinating EnzymesIBA 10/2021 - 05/2006
4	EnzymesIBA 07/2021 - 12/2006
4	sharpinIBA 01/2016 - 03/2011
3	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2021 - 01/2019
3	InterferonsIBA 11/2020 - 07/2007
3	Ligases (Synthetase)IBA 01/2017 - 02/2010
2	Pharmaceutical PreparationsIBA 05/2021 - 10/2006
2	Antiviral Agents (Antivirals)IBA 01/2021 - 11/2020
2	CytokinesIBA 01/2021 - 01/2017
2	Type I Tumor Necrosis Factor ReceptorsIBA 01/2020 - 12/2014
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2020 - 12/2014
2	Amino Acids FDA Link 04/2016 - 04/2015
2	Glucose (Dextrose)FDA LinkGeneric 04/2016 - 11/2002
2	Protein Kinases (Protein Kinase)IBA 12/2014 - 02/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2009 - 01/2009
2	NF-kappa B (NF-kB)IBA 03/2009 - 02/2008
2	Protons (Proton)IBA 07/2005 - 11/2002
2	SugarsIBA 07/2005 - 11/2002
1	LipidsIBA 01/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2021
1	Actin-Related Protein 2-3 Complex (Arp2 3 Complex)IBA 11/2021
1	ForminsIBA 11/2021
1	Interleukin-1 (Interleukin 1)IBA 10/2021
1	Serine (L-Serine)FDA Link 10/2021
1	Vitamin D3 24-HydroxylaseIBA 07/2021
1	Cholecalciferol (Vitamin D3)FDA Link 07/2021
1	Temozolomide (Temodar)FDA LinkGeneric 07/2021
1	Calcitriol (Calcijex)FDA LinkGeneric 07/2021
1	VitaminsIBA 07/2021
1	Protease Inhibitors (Protease Inhibitor)IBA 05/2021
1	SimeprevirIBA 05/2021
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2021
1	Histamine Antagonists (Antihistamines)IBA 01/2021
1	Histamine H2 ReceptorsIBA 01/2021
1	Famotidine (Pepcid)FDA LinkGeneric 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Interferon Type IIBA 11/2020
1	MicroRNAs (MicroRNA)IBA 10/2020
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2020
1	LigandsIBA 01/2020
1	Peptide Hydrolases (Proteases)FDA Link 01/2020
1	GossypolIBA 03/2019
1	Antineoplastic Agents (Antineoplastics)IBA 03/2019
1	GANT 61IBA 03/2019
1	Arsenic Trioxide (Trisenox)FDA Link 03/2019
1	Toll-Like Receptor 4IBA 01/2019
1	BiglycanIBA 01/2019
1	Small Leucine-Rich ProteoglycansIBA 01/2019
1	Histone Deacetylases (Histone Deacetylase)IBA 05/2017
1	ChromatinIBA 05/2017
1	Sirtuin 1IBA 05/2017
1	Ubiquitinated ProteinsIBA 12/2016
1	nephrinIBA 12/2016
1	Beclin-1IBA 04/2016
1	LipopolysaccharidesIBA 01/2016
1	Autophagy-Related ProteinsIBA 01/2016
1	Staphylococcal Protein A (Protein A)IBA 01/2016

Therapy/Procedure

9	Therapeutics 01/2022 - 05/2006
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2018
2	Transplantation 07/2021 - 03/2019
1	Radiotherapy 10/2021
1	Chemoradiotherapy 03/2019